The vote was months in the making for the roughly $2 trillion measure, one of the most consequential bills in decades. Now it faces a difficult path in the Senate.
Leaders pressed for a vote on a separate infrastructure bill, but the fate of both measures was in doubt amid party divisions, despite pleas from President Biden.
The House and Senate were both expected to pass short-term spending bills to fund the government, but a planned vote on a $1 trillion infrastructure bill was in limbo amid deep party divisions.
Liberal and moderate wings of the House Democratic caucus remain at odds over whether that measure should pass without work finished on the sweeping, $3.5 trillion economic package.